Bulli Pass will be closed for two days next week between Lawrence Hargrave Drive and the M1 Princes Motorway.
The closure allows for maintenance work to be carried out including the trimming of vegetation, clearing gutters and drains and maintenance of guardrails, signs and safety ramps.
The road will be closed in both directions between 9am and 3pm on Tuesday 5 and Wednesday 6 March, weather permitting.
That means motorists should use Bald Hill and Lawrence Hargrave Drive or via M1 Princes Motorway and Memorial Drive.
Residents within the closure area will have access to their properties at all times.